September 12, 2019

New HIV Research Publications

E-13 student Nicole Naiman has two recent publications relating to her research on HIV. The first, published in August 2019, appears in the Journal of Infectious Diseases, and addresses mother-to-child HIV transmission. This publication reviews an association between plasma antibody binding to the gp41 ectodomain in breastfeeding mothers to increased odds of transmission to the infant. Her next publication appears in EBioMedicine September 2019 and reviews HIV-infected infant mortality. This article also addresses HIV transmission, but focuses on antibody-dependent cellular cytotoxicity in predicting infant mortality. In a cohort of high-risk mother-infant pairs, breast milk ADCC activity was correlated with reduced risk of MTCT.